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Important safety information

What you should know before taking facial estriol. Please see the full Prescribing Information for complete safety information.

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Home delivery
FSA/HSA eligible
Compounded

Facial estriol cream

A face cream formulated with estriol, a gentle form of estrogen, to address signs of aging
Prescription medications online
Virtual care from medical experts
Personalized care plans
Insurance or self-pay options
Get care
Important safety information

Get a personalized care plan to help you address signs of aging

Access prescription face creams online, like facial estriol, tretinoin, & more.
Get care

Tackle signs of menopausal aging with facial estriol cream

Reduce appearance of fine lines
Our 0.25% estriol formulation helps stimulate synthesis of collagen & elastin, improving skin elasticity and firmness.
Hydrate and strengthen skin
Aloe Vera extract & Vitamin E moisturize skin and restore the skin barrier, helping to prevent damage that accelerates aging.
Minimize inflammation
The hypoallergenic cream base is designed to help reduce redness and irritation for a calmer and more youthful complexion.
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How we compare

Trusted medications at the right price

At Evernow, we’re committed to improving access to the medications you care about most. Through carefully selecting partner pharmacies, we lower costs & extend savings to you.

Our facial estriol is 50% cheaper than other brands and is specially formulated with powerful, high-quality ingredients like Aloe Vera and Vitamin E to promote overall skin health.

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Explore more treatments

Hormone therapy
Estradiol patch
Hormone therapy
Estradiol pills
Hormone therapy
Vaginal estrogen cream
cream
Hair loss
Oral minoxidil
Hair loss
Topical 2-in-1 finasteride
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How Evernow works

Connect with a provider
Sign up and choose how to connect with your provider—text or video. Your assigned medical expert will reach out shortly to start your care.
Get your medications
Medications in your personalized care plan can be sent to your pharmacy or delivered home. Most medications are covered by insurance.
Unlimited ongoing care
Send your provider a message at anytime to adjust your medications or raise any new questions or concerns.

Two ways to access expert menopause care

From one-time video visits to ongoing membership, you have the 
freedom to choose the personalized care that fits your needs.

Pay-per-visit

One-time virtual visit with a menopause provider
Insurance-eligible
Book a virtual visit

Membership

Unlimited ongoing access to menopause care
Starts at $35/month
Access unlimited care
Now accepting insurance for video visits:
BlueCross BlueShield
Anthem
UnitedHealth
Aetna
BlueCross BlueShield
Anthem
UnitedHealth
Aetna
BlueCross BlueShield
Anthem
UnitedHealth
Aetna
BlueCross BlueShield
Anthem
UnitedHealth
Aetna

Real results from real women

I’m starting to see a difference in my skin. It looks younger!

Verified Evernow member

Wow!! This face cream is amazing. I already see a difference.

Verified Evernow member

I recommend it to every woman I know in my age group!

Verified Evernow member

I have improved so much since I started treatment! Thank you. I really appreciate this!

Verified Evernow member

She's helpful, and cost effective!! Thank you!!!

Verified Evernow member

Facial Estriol FAQ

What is facial estriol cream?

Facial estriol cream is a topical estrogen cream for women experiencing skin changes due to menopause. As estrogen levels drop, skin can become thinner, drier, less elastic, and more prone to wrinkles. Facial estriol helps by providing localized estrogen, which boosts collagen production and improves skin firmness, elasticity, and moisture retention. This can reduce wrinkles, pore size, and dullness, leading to healthier, more youthful-looking skin.

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How does facial estriol cream work?

Facial estriol cream delivers estrogen directly to the skin, stimulating estrogen receptors to boost collagen and elastin production. This helps improve firmness, reduce wrinkles and pore size, and enhance moisture retention—targeting age-related skin changes linked to menopause.

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Who is facial estriol cream for?

For any woman seeking to reverse the effects of estrogen deficiency in the skin due to menopause, perimenopause, or aging—such as loss of collagen, decreased elasticity, and dryness—it can be used alone or alongside your existing menopause treatment plan. Consult your provider to determine if facial estriol is right for you.

What does it mean that this facial estriol is 'compounded'?

Compounded medications are custom-made by licensed U.S. pharmacies when standard options aren’t suitable. This facial estriol formula, like most compounded products, is not FDA approved and hasn’t been evaluated for safety or effectiveness by the FDA.

How do I get a prescription for facial estriol through Evernow?

Click Get Care and select your preferred type of care - a virtual visit or membership. You'll connect with a licensed clinician trained in menopause to develop a personalized care plan. Any medications you are prescribed can be sent to your local pharmacy or delivered to your home.

Do you accept insurance or FSA/HSA?

Yes. We accept insurance for video visits from major plans like UnitedHealthcare, Aetna, Anthem, and Blue Cross Blue Shield. Medications are also covered by commercial insurance if picked up at your local pharmacy. Most out of pocket costs with Evernow are also FSA/HSA eligible.

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