The estradiol patch is typically well tolerated, but there are some common side effects to be aware of. Nausea, headache, abdominal bloating, breast pain, vaginal spotting, and irritation at the placement site can occur. These side effects are typically time-limited and go away in the first few months of use.
Use of estrogen may be associated with an increased risk of heart attack, stroke, blood clots in the legs or lungs, breast cancer, uterine cancer, or dementia. Evernow prescribes the generic equivalent of Vivelle-Dot. Be sure to check out the safety information for Vivelle-Dot, and talk to your Evernow medical provider about possible contraindications, especially if you have a history of estrogen-sensitive cancer, undiagnosed vaginal bleeding, coronary heart disease, blood clots, or stroke.