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Important safety information

Your Evernow provider will determine which vaginal estradiol tablet is right for you. Please make sure to read all of the important safety information included in your medication packaging before starting this medication. If you are concerned that you are having side effects related to the medication, please contact your Evernow medical provider through our platform.

FDA-Approved
Bioidentical
Insurance eligible

Vaginal estradiol (estrogen) tablets

A hormonal treatment that helps relieve genitourinary syndrome of menopause (GSM)
Relieve menopausal symptoms
Connect with a provider within 24 hours
Prescriptions covered by most insurance
Pickup at your local pharmacy
HSA/FSA eligible membership — starting at $35/month
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cream
Get Free vaginal estrogen cream* (worth up to $480/year)
with a multi-month membership
*Must medically qualify and be on a 3-or-12-month plan
Learn more
What it is

Vaginal estradiol (estrogen) tablets are an FDA-approved treatment that helps relieve symptoms related to genitourinary syndrome of menopause (GSM). This describes menopausal symptoms including genital symptoms (ie. vaginal dryness, burning and irritation), sexual symptoms (ie. painful sex, lack of lubrication, vulvar irritation) and urinary symptoms (ie. frequent urination, urgency and/or recurrent UTIs).

Vaginal estradiol (estrogen) tablets are an FDA-approved treatment that helps relieve symptoms related to genitourinary syndrome of menopause (GSM). This describes menopausal symptoms including genital symptoms (ie. vaginal dryness, burning and irritation), sexual symptoms (ie. painful sex, lack of lubrication, vulvar irritation) and urinary symptoms (ie. frequent urination, urgency and/or recurrent UTIs).

What to expect

The time it takes to alleviate menopausal symptoms with vaginal estadiol tablets will vary by person. Many women start to experience the benefits within a few weeks of starting treatment but for some women it may take a a 2-3 months to see significant improvement in their symptoms.

The time it takes to alleviate menopausal symptoms with vaginal estadiol tablets will vary by person. Many women start to experience the benefits within a few weeks of starting treatment but for some women it may take a a 2-3 months to see significant improvement in their symptoms.

How to use

Typically, during the first two weeks of treatment, you will place a tablet every night immediately before bed. After this 2-week “loading dose”, it is common to transition to 2 nights a week. For specific information on usage, consult your provider and reference the packaging insert(s) included with your medication.

Typically, during the first two weeks of treatment, you will place a tablet every night immediately before bed. After this 2-week “loading dose”, it is common to transition to 2 nights a week. For specific information on usage, consult your provider and reference the packaging insert(s) included with your medication.

Important safety information
cream
Get Free vaginal estrogen cream* (worth up to $480/year)
with a multi-month membership
*Must medically qualify and be on a 3-or-12-month plan
Learn more
The Science Behind

Vaginal estradiol tablets can relieve common menopause symptoms

Recurrent UTIs
Incontinence
Vaginal Dryness
Painful Sex
Urinary Discomfort
Recurrent UTIs
Incontinence
Vaginal Dryness
Painful Sex
Urinary Discomfort

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FAQs

What is the vaginal estradiol (estrogen) tablet?

Vaginal estradiol tablets are an FDA-approved prescription medication designed to treat symptoms associated with genitourinary syndrome of menopause (GSM). These include vaginal atrophy, vaginal dryness, itching, painful intercourse and other urinary complaints commonly associated with menopause.

How does the vaginal estradiol tablet work?

Vaginal estradiol tablets are inserted into the vagina and designed to deliver estradiol locally to the vaginal tissues. It works by helping to replenishing estrogen levels in that area, thereby restoring vaginal moisture, improving the health of the vaginal lining, and alleviating symptoms of vaginal atrophy often associated with menopause.

When should I expect to see results with vaginal estradiol tablets?

The time it takes for vaginal estradiol tablets to alleviate menopausal symptoms, like vaginal dryness and painful sex, can vary from person to person. Many women report experiencing relief within a few weeks of starting treatment, while others may take longer to notice a significant improvement. It's essential to discuss expectations and progress with your Evernow provider, as the response to estradiol can differ based on individual factors and the specific symptoms being addressed.

What is the typical dosage of the vaginal estradiol tablet?

Dosage of vaginal estradiol tablets for managing menopausal symptom management varies depending on the brand and the individual's needs. Typical dosage usually ranges from 0.5 to 1 milligram daily, with individual adjustments made by your Evernow provider based on your specific needs and response to the treatment. It is important to adhere to the prescribed dosage and schedule provided by your Evernow provider.

How do I know if the vaginal estradiol tablet for menopause symptoms is right for me?

To determine if vaginal estradiol tablets are appropriate for you in managing symptoms of menopause, consult with your Evernow provider. They will consider your specific symptoms, medical history, and overall health to help you make an informed decision and discuss potential risks and benefits.

What are possible side effects of the vaginal estradiol tablet?

Vaginal estradiol tablets, like any medication, can cause side effects. Common side effects of vaginal estradiol tablets used for hormone replacement therapy during menopause, may include: vaginal irritation (including itching, burning, or discomfort in the vaginal area) and changes in vaginal discharge (including increased discharge or changes in consistency). Less common, but more serious side effects may include allergic reactions such as rash, itching, swelling, severe dizziness or trouble breathing. Consulting your Evernow provider about any concerns or side effects is crucial for appropriate management and evaluation of the treatment's safety.

What are common contraindications of vaginal estradiol tablets?

Vaginal estradiol tablets are generally contraindicated in individuals with a history of certain cancers (like breast cancer), undiagnosed vaginal bleeding, or those allergic to any ingredients in the medication.

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