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Important safety information

Your Evernow provider will determine which estradiol patch is right for you. Please make sure to read all of the important safety information included in your medication packaging before starting this medication. If you are concerned that you are having side effects related to the medication, please contact your Evernow medical provider through our platform.

FDA-Approved
Bioidentical
Insurance eligible

Estradiol (estrogen) patch

A transdermal estrogen patch, proven effective for treating common symptoms of menopause.
Relieve menopausal symptoms
Connect with a provider within 24 hours
Prescriptions covered by most insurance
Pharmacy pickup or at-home delivery
HSA/FSA eligible membership — starting at $35/month
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cream
Get Free vaginal estrogen cream* (worth up to $480/year)
with a multi-month membership
*Must medically qualify and be on a 3-or-12-month plan
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What it is

FDA-approved Estradiol, as part of a menopausal hormone therapy regimen, is the most effective treatment for the common symptoms (e.g., hot flashes, night sweats, insomnia, vaginal dryness) of menopause. Estradiol patches are placed on the skin and absorbed transdermally.

FDA-approved Estradiol, as part of a menopausal hormone therapy regimen, is the most effective treatment for the common symptoms (e.g., hot flashes, night sweats, insomnia, vaginal dryness) of menopause. Estradiol patches are placed on the skin and absorbed transdermally.

What to expect

The time it takes to alleviate menopausal symptoms with estradiol patches will vary by person. Many women start to experience the benefits within a few weeks of starting treatment, including a reduction in hot flashes and night sweats, more control over their mood, and better sleep. For some women it may take a a 2-3 months to see significant improvement in their symptoms.

The time it takes to alleviate menopausal symptoms with estradiol patches will vary by person. Many women start to experience the benefits within a few weeks of starting treatment, including a reduction in hot flashes and night sweats, more control over their mood, and better sleep. For some women it may take a a 2-3 months to see significant improvement in their symptoms.

How to use

Estradiol patches are very easy to use. Generally, you place the patch on your skin like a bandaid in either the lower abdomen and upper buttock. Most women rotate placement each time they replace the patch to help prevent irritation. For specific information on usage, consult your provider and reference the packaging insert(s) included with your medication.

Estradiol patches are very easy to use. Generally, you place the patch on your skin like a bandaid in either the lower abdomen and upper buttock. Most women rotate placement each time they replace the patch to help prevent irritation. For specific information on usage, consult your provider and reference the packaging insert(s) included with your medication.

Important safety information
cream
Get Free vaginal estrogen cream* (worth up to $480/year)
with a multi-month membership
*Must medically qualify and be on a 3-or-12-month plan
Learn more
The Science Behind

Estradiol patches can relieve common menopause symptoms

Hot Flashes
Night Sweats
Vaginal Dryness
Low Libido
Weight Changes
Sleep Issues
Mood Swings
Brain Fog
Hair loss
Dry Skin
Anxiety
Depression
Hot Flashes
Night Sweats
Vaginal Dryness
Low Libido
Weight Changes
Sleep Issues
Mood Swings
Brain Fog
Hair loss
Dry Skin
Anxiety
Depression

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A bioidentical, FDA-approved estrogen-based vaginal cream proven effective for treating genitourinary syndrome of menopause (GSM).

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A non-hormonal prescription medication proven to reduce the number and severity of day and night hot flashes.

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FAQs

What is the estradiol (estrogen) patch?

The estradiol patch is a form of hormone replacement therapy used to deliver estrogen through the skin directly into the bloodstream.

How does the estradiol patch work?

The estradiol patch delivers estrogen (specifically estradiol) through the skin into the bloodstream. By maintaining steady estrogen levels in the body, it helps alleviate symptoms of menopause, such as hot flashes and vaginal dryness, providing relief by supplementing the body's estrogen levels. Additionally, it by passes liver metabolism which helps reduce overall risks.

When should I expect to see results with the estradiol patch?

The time it takes for estradiol patches to alleviate menopausal symptoms can vary from person to person. Many women report experiencing relief within a few weeks of starting treatment, while others may take longer to notice a significant improvement. It's essential to discuss expectations and progress with your Evernow provider, as the response to estradiol can differ based on individual factors and the specific symptoms being addressed.

What is the typical dosage of the estradiol patch?

Dosage of estradiol patches for menopausal symptom management varies depending on the brand and the individual's needs. Typically, estradiol patches come in various strengths, such as 0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, or 0.1 mg/day. Exact dosages and individual adjustments will be made by your Evernow provider based on your specific needs and response to the treatment. It is important to adhere to the prescribed dosage and schedule provided by your Evernow provider.

How do I know if the estradiol patch for menopause symptoms is right for me?

To determine if the estradiol patch is appropriate for you in managing symptoms of menopause, consult with your Evernow provider. They will consider your specific symptoms, medical history, and overall health to help you make an informed decision and discuss potential risks and benefits.

Where to apply the estradiol patch?

The patch is easy to use. It can be placed on your body like a bandaid by pressing and spreading the patch out firmly with the palm of your hand. To keep your patch in place, position the patch in an area that won’t be irritated by clothing or crease from movement (ideal placements are the lower abdomen and on the upper buttocks below the panty line). It also helps to make sure that the site of application is free of any lotion, oil, and powders.

Which brands of estradiol patches do you prescribe?

Our providers prescribe both the branded and generic forms of the estradiol patch based on your needs, insurance coverage and preferences. The brand currently offered on Evernow are the Dotti estradiol patch. The brand may be selected for you when your treatment is picked up at the pharmacy based on availability. If you have specific preferences or concerns regarding your medications, please raise them with your Evernow provider.

What are possible side effects of the estradiol patch?

The estradiol patch, like any medication, can cause side effects. Common side effects of the estradiol patch used for hormone replacement therapy during menopause, may include skin irritation at the application site, breast tenderness, nausea, headaches, irregular bleeding/spotting, and mood changes. Less common but serious side effects may involve an increased risk of breast or uterine cancer with long-term use, and a potential risk of gallbladder disease. Consulting your Evernow provider about any concerns or side effects is crucial for appropriate management and evaluation of the treatment's safety.

What are common contraindications for the estradiol patch?

Common contraindications for the estradiol patch include a history of blood clots, estrogen-sensitive cancers (like breast cancer), liver disease, or undiagnosed vaginal bleeding.

What strength of estradiol patches do you prescribe?

Our providers prescribe a range of strengths of the estradiol patch based on your needs. The strengths currently offered on Evernow are 0.025mg, 0.0375mg, 0.05mg, 0.075mg and 0.1mg. If you have specific preferences or concerns regarding your medications, please raise them with your Evernow provider.

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