Important safety information
Your Evernow provider will determine which vaginal estradiol cream is right for you. Please make sure to read all of the important safety information included in your medication packaging before starting this medication. If you are concerned that you are having side effects related to the medication, please contact your Evernow medical provider through our platform.
Vaginal estradiol (estrogen) cream

Key benefits of vaginal estrogen

Localized for minimal absorption
Relieve menopause symptoms
Safe for proactive use
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Vaginal Estrogen FAQs
It is an FDA-approved vaginal treatment that helps relieve genitourinary syndrome of menopause (GSM). Vaginal cream is made of 0.1% estradiol cream and is bioidentical.
Vaginal estrogen is absorbed through the vagina and comes in the form of a cream or a tablet. It directly treats the root cause of symptoms by returning your estrogen levels to normal to restore tissue, blood flow, collagen, and function. Unlike systemic hormone therapy, pills, or patches, it works at the source and specifically on GSM symptoms.
Vaginal estradiol cream is for individuals experiencing symptoms of genitourinary syndrome of menopause (GSM), such as vaginal dryness, irritation, burning, or pain during sex. It’s typically prescribed for those who need localized estrogen therapy rather than systemic hormone treatment.
Yes. Vaginal estradiol cream is FDA-approved for the treatment of vaginal dryness, irritation, and painful sex due to menopause. It delivers a low dose of estrogen directly to vaginal tissues.
Bioidentical estrogen has the same molecular structure as the estrogen your body produces naturally. It is plant-derived and used in many FDA-approved HRT formulations.
Click Get Care and select your preferred type of care - a virtual visit or membership. You'll connect with a licensed clinician trained in menopause to develop a personalized care plan. Any medications you are prescribed can be sent to your local pharmacy or delivered to your home.
Yes. We accept insurance for video visits from major plans like UnitedHealthcare, Aetna, Anthem, and Blue Cross Blue Shield. Medications are also covered by commercial insurance if picked up at your local pharmacy. Most out of pocket costs with Evernow are also FSA/HSA eligible.